INFANTS AVAILABLE AT FIRST FOLLOW UP (n = 62)

Outcome measures at first follow up

IS group (n = 32)  114±9  108.0±2.3  5 (15.6)  1 (3.1)  26 (81.25)  38.5±1.6  4663±535  54.4±2.3 
P group (n = 30)  110±11  124.1±2.5  6 (20.0)  1 (3.3)  23 (76.7)  38.4±1.8  4771±469  54.9±2.2 
Mean difference (95% CI)  3.6 (−1.7 to 8.4)  –  –  –  –  0.12 (−0.7 to 1.0)  −108 (−364 to 148)  −0.48 (−1.6 to 0.6) 
p value  0.19  0.356  0.950  0.700  0.954  0.398 
Change in outcome measures from baseline to first follow up

IS group (n = 32)  −1.4±11  −64.2±91.2  –  2.1±0.6  875.7±282.7  3.0±1.1 
P group (n = 30)  −6.8±9  −65.0±119.8  –  2.3±0.7  912.3±224.0  3.0±1.3 
Mean difference (95% CI)  5.3 (0.2 to 10.5)  0.78 (−53.1 to 54.6)  –  −0.17 (−0.48 to 0.14)  −36.7 (−166.8 to 93.4)  0.05 (−0.54 to 0.64) 
p value  0.042  0.274  –  0.280  0.575  0.871 
      
INFANTS AVAILABLE AT SECOND FOLLOW UP (n = 26)

Outcome measures at second follow up

IS group (n = 13)  117±9  83.8±2.0  4 (30.7)  1 (7.7)  8 (61.5)  40.5±1.8  5669±475  58.9±2.9 
P group (n = 13)  107±12  88.4±2.6  3 (23.1)  1 (7.7)  9 (69.2)  40.9±2.1  5523±370  57.3±2.0 
Mean difference (95% CI)  9.8 (0.9 to 18.9)  –  –  –  –  −0.238 (−1.8 to 1.3)  148 (−199 to 491)  1.6 (−0.4 to 3.5) 
p value  0.03  0.681  0.736  0.310  0.390  0.108 
Change in outcome measures from baseline to second follow up

IS group (n = 13)  1.4  −121.1  –  3.8±1.0  1684.6±535  6.6±2.1 
P group (n = 13)  −6.8  −111.3  –  4.5±1.4  1653.8±260  5.2±1.3 
Mean difference (95% CI)  8.2 (−0.4 to 16.8)  −9.61 (−113 to 94)  –  −0.75 (−1.76 to 0.26)  30.7 (−310 to 371)  −1.33 (−0.07 to 2.73) 
p value  0.062  0.837  –  0.061  0.854  0.138 
Adjusted† change in infant haemoglobin

Variable

b

SE (b)

95% CI for b

p value

R^{2}

Ftest: p value

First follow up (n = 62)

Group (0 = iron,1 = placebo)  4.66  2.07  0.052 to 0.880  0.024  0.471  <0.001 
Second follow up (n = 26)

Group (0 = iron,1 = placebo)  8.60  3.25  0.180 to 1.540  0.016  0.582  0.003 